Full Title: Atorvastatin Decreases the Coenzyme Q10 Level in the Blood of Patients at Risk for Cardiovascular Disease and Stroke
Tatjana Rundek, MD; Ali Naini, PhD; Ralph Sacco, MD; Kristen Coates, MS; Salvatore DiMauro, MD
Arch Neurol. 2004;61:889-892.
ABSTRACT
Background: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are widely used for the treatment of hypercholesterolemia and [...]
Caso G, Kelly P, McNurlan MA, Lawson WE.
Department of Surgery, Division of Cardiology, Stony Brook University, Stony Brook, NY, USA. giuseppe.caso@stonybrook.edu
Treatment of hypercholesterolemia with statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) is effective in the primary and secondary prevention of cardiovascular disease. However, statin use is often associated with a variety of muscle-related symptoms or myopathies. [...]
Coenzyme Q10 has shown the ability to protect nerve cells and potentially lower the risk of various degenerative diseases.Cells in the brain and nervous system depend on optimal mitochondrial function for energy. A research study published in the journal Neurobiology of Disease showed that oxidative stress causes mitochondria to produce excessive free radicals, leading to [...]
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